Document Detail

99mTc-pyrophosphate imaging in experimental mesenteric infarction: relationship of tracer uptake to the degree of ischemic injury.
MedLine Citation:
PMID:  212779     Owner:  NLM     Status:  MEDLINE    
Four-hour balloon occlusion of the cranial mesenteric artery in 13 dogs produced a spectrum of widespread ischemic injury to the small bowel ranging from superficial mucosal infarction to transmural infarction. Twenty-four hours after the beginning of balloon occlusion, 15 mCl of 99mTc-pyrophosphate was injected into the cranial mesenteric artery in 8 dogs and into a peripheral vein in 5. Gamma camera imaging of the abdomen followed three hours later. Four of 8 dogs injected intra-arterially showed positive images with full-thickness mucosal or transmural infarction. The 4 intravenously injected dogs with positive images had transmural infarction. Only minimal ischemic injury with superficial mucosal infarction was found in the 5 dogs with negative images. Tracer uptake per gram infarcted tissue was highest after intra-arterial injection. It was concluded that 99mTc-pyrophosphate allows external imaging of extensive intestinal infarctions after both intra-arterial and intravenous injection.
K H Barth; P O Alderson; J D Strandberg; H W Strauss; R I White
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Radiology     Volume:  129     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  491-5     Citation Subset:  AIM; IM    
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MeSH Terms
Diphosphates / diagnostic use
Infarction / pathology,  radionuclide imaging*
Intestines / blood supply*,  pathology,  radionuclide imaging
Mesenteric Vascular Occlusion / radionuclide imaging
Mesentery / blood supply*
Technetium / diagnostic use*
Reg. No./Substance:
0/Diphosphates; 7440-26-8/Technetium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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