Document Detail

99mTc-labelled red blood cell scintigraphy for localization of gastrointestinal bleeding in chronic renal failure.
MedLine Citation:
PMID:  9730709     Owner:  NLM     Status:  MEDLINE    
Angiodysplasia (AD) may be the source of bleeding in patients with gastrointestinal hemorrhage, with special occurrence in the elderly population and in patients with chronic renal failure (CRF). Although several techniques have been tested for its diagnosis, the gold standard is not well defined yet. We analyze the usefulness of 99mTc-labelled red blood cell (99mTc RBC) scintigraphy in the localization of bleeding from AD lesions in a cohort of 21 patients. Other investigative methods include fibrocolonoscopy examination, angiography, or diagnostic laparotomy. Group A (AD and CRF): 11 patients. Group B (AD without CRF): 10 patients. 99mTc RBC scintigraphy showed 88.9% sensitivity and specificity in group A, while in group B it had 100% sensitivity and specificity. Arteriography showed 100% sensitivity and specificity. On the contrary, fibrocolonoscopy had a very low sensitivity (30%). Our results suggest that 99mTc RBC scintigraphy may be the preferred diagnostic tool for AD, especially in patients with CRF, in whom arteriography may accelerate the decline of renal function.
A Oliveras; J Aubia; H Cao; J M Puig; F Barbosa; M Mir; A Orfila; J Lloveras; J Masramon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephron     Volume:  80     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-10-30     Completed Date:  1998-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  76-8     Citation Subset:  IM    
Department of Nephrology, Hospital del Mar, Barcelona, Spain.
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MeSH Terms
Aged, 80 and over
Gastrointestinal Hemorrhage / complications*,  radiography,  radionuclide imaging*
Kidney Failure, Chronic / complications*,  radionuclide imaging
Middle Aged
Sensitivity and Specificity
Technetium / diagnostic use*
Transplantation, Autologous
Reg. No./Substance:

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