Document Detail

99mTc-labelled pyrophosphate myocardial scanning in experiment and in clinical practice.
MedLine Citation:
PMID:  6277567     Owner:  NLM     Status:  MEDLINE    
A survey is presented of research results of pyrophosphate myocardial scanning in 130 dogs and 150 patients with various myocardial lesions. The results of experiments in animals were immediately applied in clinical practice. The results showed that acute transmural myocardial lesions yielded practically in all instances positive scintigraphic findings. The findings in nontransmural infarctions were less convincing--they were positive in 60% of cases. Positive scintigraphic findings were also obtained in 80% of dogs with experimentally induced temporary ischaemia, and in 80% of dogs with experimentally induced dystrophy of the myocardium. In patients with angina pectoris positive findings were obtained in 1/3 of the cases, and in patients with cardiomyopathies, in 1/3 to 1/4 of the cases (in dependence on the etiology of the cardiomyopathy). It appears that 99mTc-PYP is a highly sensitive, but nonspecific, detector of myocardial lesions.
J Vizda; F Duska; J Kubícek; P Kafka; J Novák; Y Mazurová
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  23     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1981  
Date Detail:
Created Date:  1982-05-27     Completed Date:  1982-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  457-66     Citation Subset:  IM    
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MeSH Terms
Angina Pectoris / radionuclide imaging
Cardiomyopathies / radionuclide imaging
Coronary Artery Bypass
Coronary Disease / radionuclide imaging*
Diphosphates / diagnostic use
Myocardial Infarction / radionuclide imaging
Myocardium / pathology
Technetium / diagnostic use
Technetium Tc 99m Pyrophosphate
Reg. No./Substance:
0/Diphosphates; 0/Technetium Tc 99m Pyrophosphate; 7440-26-8/Technetium

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