Document Detail

99mTc-DTPA--a useful clinical tool for the measurement of glomerular filtration rate.
MedLine Citation:
PMID:  6761859     Owner:  NLM     Status:  MEDLINE    
The single injection 99mTc-DTPA clearance was compared with the inulin clearance performed with the constant infusion technique in 22 subjects. There was a good correlation between these two methods (r = 0.968, p less than 0.001). Although the single injection technique calculated by one compartment model is not accurate enough for research purposes, it seems to work well in routine clinical practice for the measurement of glomerular filtration rate using 99mTc-DTPA as a tracer substance. The performance is simple, it needs only a few blood samples, nor does it need any urine collection, the radiation dose is low and it seems to be more accurate than the endogenous creatinine clearance.
K Huttunen; N P Huttunen; A Koivula; A Ahonen; R Puukka
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  16     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1982  
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  237-41     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Glomerular Filtration Rate*
Inulin / administration & dosage,  diagnostic use,  metabolism
Kidney Function Tests
Metabolic Clearance Rate
Middle Aged
Pentetic Acid / administration & dosage,  diagnostic use*,  metabolism
Technetium / administration & dosage,  diagnostic use*,  metabolism
Technetium Tc 99m Pentetate
Reg. No./Substance:
65454-61-7/Technetium Tc 99m Pentetate; 67-43-6/Pentetic Acid; 7440-26-8/Technetium; 9005-80-5/Inulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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