| (99m)Tc-DPD-SPECT/CT predicts the outcome of imaging-guided diagnostic anaesthetic injections: A prospective cohort study. | |
| | |
MedLine Citation:
|
PMID: 20951520 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
PURPOSE: We hypothesized that bone SPECT combined with multiplanar reconstructed CT can identify and target the pain-inducing focus in the foot and can be used to successfully guide anaesthetic infiltrations. Therefore we prospectively investigated feasibility and predictive value of bone SPECT/CT for image guided diagnostic infiltrations in patients with chronic foot pain. METHODS: All patients received a standardized bone SPECT/CT of both feet. The scintigraphically most active structures were subsequently infiltrated with local anaesthetics under CT-guidance. The pre- and post-infiltration pain intensity was measured using the visual analogue scale (VAS). Then, we assessed (i) the agreement on pain originating structures determined by standard clinical assessment versus SPECT/CT and (ii) the predictive value of SPECT-CT in groups with and without agreement. RESULTS: 27 of 30 participants reported a pain reduction on VAS of 50% or more, resulting in a response rate of 90%. When assessing the agreement on pain initiating structures determined by standard clinical assessment versus SPECT/CT, we found a disagreement in 16 of 30 (53%) cases. Particularly, disagreement appeared in all 9 participants with symptoms located in the mid-foot (100%). In participants with hind-foot pathology, disagreement was found in 7 of 21 cases (33%). CONCLUSION: The present study shows the feasibility of (99m)Tc-DPD-SPECT/CT guided infiltration of osseous structures of patients with chronic foot pain. (99m)Tc-DPD-SPECT/CT had a higher predictive value on the clinical outcome than the clinical assessment. In the clinical setting (99m)Tc-DPD-SPECT/CT might overrule the clinical assessment in case of disagreement on the target lesion. |
| | |
Authors:
|
Martin Kretzschmar; Martin Wiewiorski; Helmut Rasch; Augustinus L Jacob; Deniz Bilecen; Martin A Walter; Victor Valderrabano |
Publication Detail:
|
Type: Journal Article Date: 2010-10-15 |
Journal Detail:
|
Title: European journal of radiology Volume: 80 ISSN: 1872-7727 ISO Abbreviation: Eur J Radiol Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-11-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
|
Languages: eng Pagination: e410-5 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Division of Interventional Radiology, University Hospital, Petersgraben 4, CH-4031 Basel, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Measurement of renal volume using respiratory-gated MRI in subjects without known kidney disease: In...
Next Document: Unsupervised MRI segmentation of brain tissues using a local linear model and level set.