| 99Tc Nanocolloid sentinel node procedure in thyroid carcinoma. | |
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MedLine Citation:
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PMID: 18626655 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purposes of this study were to investigate the efficacy of radiocolloid lymphoscintigraphy and of handheld gamma probe procedure for sentinel lymph node biopsy (SLNB) in papillary thyroid carcinoma (PTC) and to evaluate its results in clinical staging. MATERIALS AND METHODS: Sixty-five PTC consecutive patients entered the study. Patients underwent radiocolloid lymphoscintigraphy before surgery. Intraoperative sentinel lymph node (SLN) localization was performed using a handheld gamma probe. They were followed up at 2, 6 months, and yearly. RESULTS: SLN metastases were diagnosed in 52%. Fifty-one patients underwent ablative 131-I therapy. The mean Tireoglobulin level in N0 vs N1 cases was 2.2 ng/ml vs 4.73 (p = 0.03) and 0.68 vs 2.1 ng/ml (p = 0.005) before and after 131-I therapy, respectively. CONCLUSIONS: In patients classified N0 by SLNB, ablative 131-I therapy could be avoided. |
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Authors:
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Isabella Merante Boschin; Antonio Toniato; Andrea Piotto; Eric Casal Ide; Dario Casara; AnnaMaria Guolo; Domenico Rubello; MariaRosa Pelizzo |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-07-15 |
Journal Detail:
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Title: Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie Volume: 393 ISSN: 1435-2451 ISO Abbreviation: Langenbecks Arch Surg Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-08 Completed Date: 2009-05-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808285 Medline TA: Langenbecks Arch Surg Country: Germany |
Other Details:
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Languages: eng Pagination: 705-8 Citation Subset: IM |
Affiliation:
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Surgical Pathology, University of Padua School of Medicine, Istituto Oncologico Veneto (IOV), Padua, Italy. isabella.meranteboschin@unipd.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Papillary / pathology*, radionuclide imaging*, radiotherapy, surgery Combined Modality Therapy Female Follow-Up Studies Humans Iodine Radioisotopes / therapeutic use Lymph Nodes / pathology, radionuclide imaging Male Middle Aged Neoplasm Staging Radionuclide Imaging / methods* Radiotherapy, Adjuvant Sensitivity and Specificity Sentinel Lymph Node Biopsy / methods* Technetium Tc 99m Aggregated Albumin / diagnostic use* Thyroid Neoplasms / pathology*, radionuclide imaging*, radiotherapy, surgery Thyroidectomy Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes; 0/Technetium Tc 99m Aggregated Albumin; 0/technetium Tc 99m nanocolloid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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