Document Detail


A 95-year-old woman with leucocytosis and eosinophilia: anaplastic carcinoma in an ectopic thyroid.
MedLine Citation:
PMID:  22767520     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 95-year-old woman had been treated over the past 8 years for progressive dysphagia. When her condition worsened, blood tests revealed the presence of leucocytosis and eosinophilia in the absence of anaemia or thrombocytopenia. Within 11 days of diagnosis, the patient died of respiratory failure. Necropsy showed normal thyroid tissue and an absence of infectious disease. However, an upper mediastinal tumour was found and was histopathologically diagnosed as a neoplastic transformation of the ectopic thyroid. Only 1% of endothoracic goitres present as ectopic or autonomous goitre with no parenchymal or vascular connection to the thyroid gland. This case represents a very rare situation in which a leukemoid reaction and peripheral hypereosinophilia were observed as a manifestation of an anaplastic thyroid carcinoma in an ectopic mass.
Authors:
Einstein Francisco Camargos; Marcela Basso Pandolfi; Maria Alice V Toledo; Juliana Lima Quintas; Sebastião Moreira-Junior; Ana Emília Borges de Azevedo; Alexandre Cavalca Tavares
Publication Detail:
Type:  Journal Article     Date:  2010-08-31
Journal Detail:
Title:  BMJ case reports     Volume:  2010     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2010  
Date Detail:
Created Date:  2012-07-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Affiliation:
Geriatric Medical Centre, University Hospital, Brasilia University, Brasilia, Brazil.
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