| A 9-year review of dystonia from a movement disorders clinic in Singapore. | |
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MedLine Citation:
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PMID: 16420396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical features of dystonia have not been evaluated in Southeast Asia. We therefore investigated the clinical spectrum and characteristics of dystonia in Singapore, a multi-ethnic Southeast Asian country comprising 77% Chinese, 14% Malays, and 8% Indians. We identified all dystonia patients from the Movement Disorders database and Botulinum Toxin clinic between 1995 and November 2004. Their medical records were reviewed to verify the diagnosis of dystonia and obtain demographic and clinical data using a standardized data collection form. A total of 119 (73%) patients had primary dystonia whilst 45 (27%) had secondary dystonia. There were 77% Chinese, 9% Malays, and 8% Indians. The most common focal dystonia were cervical dystonia (47%), writer's cramp (32%), and blepharospasm (11%). There was no significant difference in the distribution of dystonia between the different races. Males were noted to have earlier onset of dystonia overall. There was a significant male predominance in primary dystonia overall (M:F 1.6:1, P=0.008) and in the subgroup of focal dystonia (M:F 1.6:1, P=0.037). This contrasts with previous studies that found a female predominance. The role of genetic, hormonal, and environmental factors and their interactions need to be investigated to better understand the gender differences in the occurrence of dystonia. |
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Authors:
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R D G Jamora; A K Y Tan; L C S Tan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: 13 ISSN: 1351-5101 ISO Abbreviation: Eur. J. Neurol. Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2006-01-19 Completed Date: 2006-04-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: England |
Other Details:
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Languages: eng Pagination: 77-81 Citation Subset: IM |
Affiliation:
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Department of Neurology, National Neuroscience Institute-TTSH Campus, Singapore. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dystonic Disorders
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epidemiology*,
etiology* Female Humans Male Movement Disorders / complications*, epidemiology* Sex Factors Singapore / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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