Document Detail

9. Food allergy.
MedLine Citation:
PMID:  12592300     Owner:  NLM     Status:  MEDLINE    
Food allergies affect as many as 6% of young children, most of whom "outgrow" the sensitivity, and about 2% of the general population. Although any food may provoke a reaction, relatively few foods are responsible for the vast majority of food allergic reactions: milk, egg, peanuts, tree nuts, fish, and shellfish. Many of these food allergens have been characterized at a molecular level, which has increased our understanding of the immunopathogenesis of many responses and may soon lead to novel immunotherapeutic approaches. Food allergic reactions are responsible for a variety of symptoms involving the skin, gastrointestinal tract, and respiratory tract and may be due to IgE-mediated and non-IgE-mediated mechanisms. A systematic approach including history, laboratory studies, elimination diets, and often food challenges will lead to the correct diagnosis. Currently, management of food allergies consists of educating the patient to avoid ingesting the responsible allergen and to initiate therapy in case of an unintended ingestion.
Hugh A Sampson
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  111     ISSN:  0091-6749     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-19     Completed Date:  2003-03-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S540-7     Citation Subset:  AIM; IM    
Jaffe Food Allergy Institute, Medical Center, The Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA.
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MeSH Terms
Food Hypersensitivity / complications,  diagnosis,  physiopathology,  therapy*
Gastrointestinal Diseases / immunology
Skin Diseases / immunology

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