Document Detail


An 8-year single-centre experience of cardiac resynchronisation therapy: procedural success, early and late complications, and left ventricular lead performance.
MedLine Citation:
PMID:  23315159     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIMS: Despite the increasing number of device implants worldwide, little is known about the early and late complications of cardiac resynchronisation therapy (CRT) or the incidence of these complications in patients with different heart failure aetiologies. We aim to determine procedural success and early and late complications in CRT patients.METHODS AND RESULTS: All early (<90 days) and late (>90 days) complications occurring over 490 consecutive CRT procedures in 402 patients, from a large single-centre registry between 2000 and 2009 were analysed. Mean follow-up duration was 1012 ± 610 days. In addition, procedural data and long-term left ventricular (LV) lead performance were examined. The mean age of patients was 65 ± 15 years, 31% were female. The majority of devices (70%) were CRT-defibrillators. Left ventricular lead implantation was achieved after one or more than one attempt in 96.7% of patients (first procedure was successful in 95.1%). The incidence of early and late complications was 9.4% and 6.1% respectively. Infection and lead displacement were the most common complications. Dilated cardiomyopathy (DCM) was associated with significantly more complications than ischaemic cardiomyopathy (P = 0.01) and these occurred later in the DCM population. Long-term LV lead performance was comparable with that of right atrial and ventricular leads.CONCLUSION: Transvenous implantation of the LV lead is safe and achievable for CRT with high procedural success rates. For the first time we describe the late complications from CRT in different heart failure populations. This group of patients must be kept under surveillance, not only for heart failure events but also for device-related issues. The reasons for higher complication rates in DCM patients require further evaluation.
Authors:
Syed Y Ahsan; Bunny Saberwal; Pier D Lambiase; Sanjay Chaubey; Oliver R Segal; Aerokondal B Gopalamurugan; James McCready; Dominic P Rogers; Martin D Lowe; Anthony W C Chow
Related Documents :
12727149 - Association of a genetic variant of endothelial nitric oxide synthase with the 1 year c...
19411669 - Postoperative renal dysfunction and preoperative left ventricular dysfunction predispos...
2502249 - First myocardial infarctions in asian and white men.
15642869 - Vasopressin for cardiac arrest: a systematic review and meta-analysis.
10496439 - Comparison of echocardiography and radionuclide angiography as predictors of mortality ...
9744969 - Trends in the incidence of myocardial infarction and in mortality due to coronary heart...
8943459 - Cardiac tamponade in association with an atrial septal defect: echocardiographic dopple...
1525809 - St segment alternans during coronary angioplasty.
7332519 - Myocardial lactate dehydrogenase isoenzyme distribution in the normal heart.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-12
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  -     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
The Heart Hospital, Institute of Cardiovascular Sciences, 16-18 Westmoreland Street, London, W1G 8PH, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mapping of the quantitative trait locus (QTL) conferring partial resistance to rice leaf blast disea...
Next Document:  Construction of a transgenic pig model overexpressing polycystic kidney disease 2 (PKD2) gene.