| ∝7 nAChR in airway respiratory epithelial cells. | |
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MedLine Citation:
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PMID: 22300033 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This review examines the role of a7-nAChR in different types of airways epithelial cells of the normal human bronchial tree. In each of these cells a7-nAChR activation elicits a specific effect. The effect is essentially mitogenic, whereas in the airway basal cells is antiproliferative. It is postulated that a7-nAChR may have mitogenic or antiproliferative signals differentially activated in different types of airways cells and under exposure to exogenous stimuli such as nicotine. |
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Authors:
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Candida Nastrucci; Patrizia Russo |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-17 |
Journal Detail:
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Title: Current drug targets Volume: - ISSN: 1873-5592 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-2-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100960531 Medline TA: Curr Drug Targets Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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IRCCS "San Raffaele Pisana", Rome, Italy. candida.nastrucci@sanraffaele.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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