Document Detail


64-multidetector computed tomographic angiography of the canine coronary arteries.
MedLine Citation:
PMID:  21521398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Canine coronary artery angiography (CTA) was performed in four anesthetized healthy dogs using 64-multidetector computed tomography. Esmolol, a β-1 adrenergic receptor antagonist, and sodium nitroprusside, an arteriolar and venous dilator, were administered to enhance visualization of the coronary arteries by reducing heart rate and creating vasodilation. The left main coronary artery with its three main branches and the right coronary artery were visualized and subdivided in 13 segments for evaluation. Optimal reconstruction interval, expressed as percentage of the R-to-R interval, was determined at 5% in 2.9%, 35% in 1%, 75% in 21.2%, 85% in 43.3%, and 95% in 31.7% of the segments. Overall image quality was good in 41.3% of the segments and excellent in 14.4%. There was blur in 98.1%, motion in 17.3%, and stair step in 6.7% of the evaluated segments, but these artifacts did not interfere with anatomic depiction of the arteries. Cross-sectional anatomy of the coronary arteries as evaluated from the coronary CTA agreed well with gross anatomic evaluation and published information. The use of esmolol did not lead to the target heart rate of 60-65 beats/min. Nitroprusside had no significant effect on visualized length or diameter of the coronary artery branches. Coronary CTA is useful for the anatomic depiction of coronary artery branches in the dog.
Authors:
Randi Drees; Alex Frydrychowicz; Scott B Reeder; Marie E Pinkerton; Rebecca Johnson
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Publication Detail:
Type:  Journal Article     Date:  2011-04-26
Journal Detail:
Title:  Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association     Volume:  52     ISSN:  1058-8183     ISO Abbreviation:  Vet Radiol Ultrasound     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-09-19     Completed Date:  2011-10-18     Revised Date:  2012-03-23    
Medline Journal Info:
Nlm Unique ID:  9209635     Medline TA:  Vet Radiol Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  507-15     Citation Subset:  IM    
Copyright Information:
© 2011 Veterinary Radiology & Ultrasound.
Affiliation:
Department of Surgical Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA. drees@svm.vetmed.wisc.edu
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-1 Receptor Antagonists / administration & dosage
Animals
Contrast Media
Coronary Angiography / veterinary*
Coronary Vessels / drug effects
Dogs*
Nitroprusside / administration & dosage
Propanolamines / administration & dosage
Tomography, X-Ray Computed / veterinary*
Vasodilator Agents / administration & dosage
Grant Support
ID/Acronym/Agency:
UL1 RR025011-03/RR/NCRR NIH HHS; UL1 RR025011-04/RR/NCRR NIH HHS; UL1 RR025011-05/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Adrenergic beta-1 Receptor Antagonists; 0/Contrast Media; 0/Propanolamines; 0/Vasodilator Agents; 15078-28-1/Nitroprusside; 84057-94-3/esmolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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