| 64-Multidetector-row spiral CT in pulmonary embolism with emphasis on incidental findings. | |
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MedLine Citation:
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PMID: 18760719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: In this retrospective study, we assess the current role and future potential of computed tomography (CT) in the diagnostic algorithm of acute pulmonary embolism (PE). MATERIALS AND METHODS: Two hundred patients underwent 64-multidetector-row spiral CT of the chest, pelvis, and thigh for suspected PE. CT scans were reviewed, and the degree of contrast enhancement and the presence of PE and/or (deep) venous thrombosis were recorded. In the case of PE, the level of thrombus was noted as central, main, or lobar. If the scan yielded a positive result for thrombosis, intravenous localization was also determined. Patient age, length of admission, clinical course, clinical indication, and incidental findings were registered as well. RESULTS: PE was detected in 60 of the 200 patients with a high clinical probability of having PE (30%). Thirty-four patients had a positive CT scan result for venous thrombosis (17%). Twenty-four of the 60 patients had proximal deep venous thrombosis (40%), and 2 patients had arm venous thrombosis (3%). Thirty-four of the 60 patients had PE without venous thrombosis (57%). Eight of the 200 patients had deep venous thrombosis without suspicion of PE (4%). The distribution of the proximal thrombi showed 15 in a central artery (25%), 13 in a main pulmonary artery (22%), and 32 in a lobar segmental artery (53%). There was diffuse allocation of the thrombus in all lobes. Furthermore, CT scan noted a total of 120 incidental findings. CONCLUSION: Our study indicates the potential clinical use of a diagnostic strategy for ruling out PE based on D-dimer testing and multidetector-row CT. A larger outcome study is needed before this approach can be adopted. |
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Authors:
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Christian Sohns; Erick Amarteifio; Samuel Sossalla; Markus Heuser; Silvia Obenauer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical imaging Volume: 32 ISSN: 1873-4499 ISO Abbreviation: Clin Imaging Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-09-01 Completed Date: 2009-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911831 Medline TA: Clin Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 335-41 Citation Subset: IM |
Affiliation:
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Department of Radiology, Georg-August-University Goettingen, Göttingen, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Age Distribution Aged Aged, 80 and over Cohort Studies Contrast Media / diagnostic use Female Humans Incidence Incidental Findings* Male Middle Aged Pulmonary Embolism / epidemiology, radiography* Radiographic Image Interpretation, Computer-Assisted* Retrospective Studies Risk Assessment Sensitivity and Specificity Severity of Illness Index Sex Distribution Tomography, Spiral Computed / methods* Venous Thrombosis / epidemiology, radiography* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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