Document Detail


A 63 kDa protein is secreted from BALB/c-3T3 cells entering the G1 phase from the G0 state.
MedLine Citation:
PMID:  3691816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 63 kDa protein is detectable in the culture fluid of mouse BALB/c-3T3 cells traversing from the G0 state to the G1 phase, whereas it is undetectable in the culture fluid of quiescent or growing BALB/c-3T3 cells. Secretion of the protein is maximal at 10 h after serum addition. G0-specific ts mutant cells (rat tsJT60) also secrete the 63 kDa protein only when the quiescent cells are stimulated by serum addition at permissive temperature. These facts indicate that the 63 kDa protein is secreted only from cells traversing from the G0 state to the G1 phase.
Authors:
S Tominaga
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  226     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-27     Completed Date:  1988-01-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  53-7     Citation Subset:  IM    
Affiliation:
Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cells, Cultured
Culture Media
Interphase*
Mice
Mice, Inbred BALB C
Molecular Weight
Mutation
Protein Biosynthesis
Proteins / isolation & purification*,  secretion
Chemical
Reg. No./Substance:
0/Culture Media; 0/Proteins

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