Document Detail


60-year old woman with extra-axial frontal mass.
MedLine Citation:
PMID:  19076782     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a 60 year-old woman presenting with visual loss of her left eye. No lymphadenopathies, fever, or weight loss were detected. Neuroimaging studies revealed an extra-axial mass along the posterior aspect of the left optic nerve. The mass was resected and showed xanthomatous histiocytes that were positive for CD-68, occasionally positive for S-100, and negative for CD-1. The lesion was diagnosed as Erdheim-Chester disease (ECD) affecting the CNS. The patient is under systemic evaluation in order to discover other ECD lesions. Microscopic findings and differential diagnoses are discussed.
Authors:
Naomi Arakaki; Miguel A Riudavets; Andrés Cervio; Marcelo Ferreira; Gustavo Sevlever
Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Brain pathology (Zurich, Switzerland)     Volume:  19     ISSN:  1750-3639     ISO Abbreviation:  Brain Pathol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9216781     Medline TA:  Brain Pathol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antigens, CD / analysis
Antigens, Differentiation, Myelomonocytic / analysis
Blindness / etiology*
Diagnosis, Differential
Erdheim-Chester Disease / complications,  diagnosis*,  metabolism
Female
Histiocytes / chemistry,  pathology*
Humans
Magnetic Resonance Imaging
Middle Aged
Optic Nerve Neoplasms / complications,  diagnosis*,  metabolism
S100 Proteins / analysis
Chemical
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, Differentiation, Myelomonocytic; 0/CD68 antigen, human; 0/S100 Proteins

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