| A 6-year review of total parenteral nutrition use and association with late-onset acute respiratory distress syndrome among ventilated trauma victims. | |
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MedLine Citation:
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PMID: 19117556 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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AIM: To establish whether total parenteral nutrition (TPN) for ventilated trauma victims is associated with late-onset acute respiratory distress syndrome (ARDS) independent of ventilation and transfusion parameters. METHOD: Intensive care unit data over 6 years from a level I centre regarding all trauma victims > or = 16 years old who underwent mechanical ventilation within the first 48 h of admission were examined. Patients were prospectively followed for late ARDS. Variables were examined for significant changes over time and independent associations with late ARDS were determined. RESULTS: Of 2346 eligible patients among whom 404 (17.2%) were exposed to TPN, 192 (8.2%) met criteria for late ARDS. The incidence of late ARDS among those exposed to TPN was 28.7% (116/404) compared with 3.9% (76/1942) among those not so exposed. Adjustments for potential confounding associated risk factors were made. CONCLUSIONS: TPN administration is independently associated with late ARDS, and its use among critically ill trauma victims should be carefully scrutinised. |
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Authors:
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David Plurad; Donald Green; Kenji Inaba; Howard Belzberg; Demetrios Demetriades; Peter Rhee |
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Publication Detail:
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Type: Journal Article Date: 2008-12-30 |
Journal Detail:
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Title: Injury Volume: 40 ISSN: 1879-0267 ISO Abbreviation: Injury Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0226040 Medline TA: Injury Country: Netherlands |
Other Details:
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Languages: eng Pagination: 511-5 Citation Subset: IM |
Affiliation:
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University of Southern California and Los Angeles County Hospital Division of Trauma/Surgical Critical Care, Los Angeles, CA 90033, USA. plurad@usc.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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