Document Detail

6-Methylcoumarin photocontact dermatitis.
MedLine Citation:
PMID:  7364969     Owner:  NLM     Status:  MEDLINE    
Sporadic cases of a severe photocontact dermatitis have appeared in the last few years following use of fruity-smelling suntan preparations and sunlight exposure. We report five such cases in women who developed severe edema and erythema of sun-exposed areas shortly after application of agents containing 6-methylcoumarin used as fragance. Routine photopatch testing was unproductive in reproducing the reaction, but immediate application of 6-methylcoumarin before ultraviolet A (UVA) radiation elicited significant positive results.
R T Jackson; L T Nesbitt; V A DeLeo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  2     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1980 Feb 
Date Detail:
Created Date:  1980-06-25     Completed Date:  1980-06-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  124-7     Citation Subset:  IM    
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MeSH Terms
Coumarins / adverse effects*
Edema / chemically induced
Erythema / chemically induced
Patch Tests
Photosensitivity Disorders / chemically induced*
Sunscreening Agents / adverse effects*
Ultraviolet Rays / diagnostic use
Reg. No./Substance:
0/Coumarins; 0/Sunscreening Agents; 92-48-8/6-methylcoumarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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