Document Detail

5-fluorouracil extravasation following port failure.
MedLine Citation:
PMID:  11272975     Owner:  NLM     Status:  MEDLINE    
A case is presented of cytotoxic extravasation as a result of an implantable venous port being perforated by a standard Huber needle. A patient receiving 5-fluorouracil via a dual reservoir port, implanted within the left chest wall, presented with hemoserous discharge from the right needle entry site. The left chest wall was warm to touch, erythematous, and swollen. Subcutaneous infiltration was suspected, and the infusion was ceased. A venogram was performed demonstrating significant extravasation around the left reservoir only. On port removal, inspection showed the Huber needle had penetrated the base plate on the left side. It is recommended that this complication be added as a possible sequelae of central venous port use.
S P Nesti; R Kovac
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of intravenous nursing : the official publication of the Intravenous Nurses Society     Volume:  23     ISSN:  0896-5846     ISO Abbreviation:  J Intraven Nurs     Publication Date:    2000 May-Jun
Date Detail:
Created Date:  2001-03-01     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804311     Medline TA:  J Intraven Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  176-80     Citation Subset:  N    
Cancer Division of Royal Perth Hospital, Perth, Australia.
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MeSH Terms
Antimetabolites, Antineoplastic / adverse effects*
Carcinoma, Signet Ring Cell / drug therapy*
Catheters, Indwelling / adverse effects*
Equipment Failure
Fluorouracil / adverse effects*
Stomach Neoplasms / drug therapy*
Reg. No./Substance:
0/Antimetabolites, Antineoplastic; 51-21-8/Fluorouracil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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