| 4D time-resolved MR angiography with keyhole (4D-TRAK): more than 60 times accelerated MRA using a combination of CENTRA, keyhole, and SENSE at 3.0T. | |
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MedLine Citation:
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PMID: 18504736 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To present a new 4D method that is designed to provide high spatial resolution MR angiograms at subsecond temporal resolution by combining different techniques of view sharing with parallel imaging at 3.0T. MATERIALS AND METHODS: In the keyhole-based method, a central elliptical cylinder in k-space is repeated n times (keyhole) with a random acquisition (CENTRA), and followed by the readout of the periphery of k-space. 4D-MR angiography with CENTRA keyhole (4D-TRAK) was combined with parallel imaging (SENSE) and partial Fourier imaging. In total, a speed-up factor of 66.5 (6.25 [CENTRA keyhole] x 8 [SENSE] x 1.33 [partial Fourier imaging]) was achieved yielding a temporal resolution of 608 ms and a spatial resolution of (1.1 x 1.4 x 1.1) mm(3) with whole-brain coverage 4D-TRAK was applied to five patients and compared with digital subtraction angiography (DSA). RESULTS: 4D-TRAK was successfully completed with an acceleration factor of 66.5 in all five patients. Sharp images were acquired without any artifacts possibly created by the transition of the central cylinder and the reference dataset. MRA findings were concordant with DSA. CONCLUSION: 4D time-resolved MRA with keyhole (4D-TRAK) is feasible using a combination of CENTRA, keyhole, and SENSE at 3.0T and allows for more than 60 times accelerated MRA with high spatial resolution. |
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Authors:
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Winfried A Willinek; Dariusch R Hadizadeh; Marcus von Falkenhausen; Horst Urbach; R Hoogeveen; Hans H Schild; Jürgen Gieseke |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 27 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-02 Completed Date: 2008-09-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1455-60 Citation Subset: IM |
Copyright Information:
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2008 Wiley-Liss, Inc |
Affiliation:
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Department of Radiology, University of Bonn, Bonn, Germany. winfried.willinek@ukb.uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms* Angiography, Digital Subtraction / methods Contrast Media / administration & dosage Feasibility Studies Female Gadolinium DTPA / diagnostic use Humans Image Enhancement / methods Image Processing, Computer-Assisted / methods* Intracranial Arteriovenous Malformations / diagnosis* Iohexol / analogs & derivatives, diagnostic use Magnetic Resonance Angiography / instrumentation, methods* Magnetics Male Middle Aged Observer Variation Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide; 80529-93-7/Gadolinium DTPA |
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