Document Detail


A 4D dose computation method to investigate motion interplay effects in scanned ion beam prostate therapy.
MedLine Citation:
PMID:  24819696     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In particle therapy, the interplay between beam scanning and target motion during treatment delivery may result in dose deterioration. Interplay effects have been studied for targets exhibiting periodic respiratory motion, however, they are not well understood for irregular motion patterns, such as those exhibited by the prostate. In this note, we propose and validate a 4D dose computation method, which enables estimation of effective dose delivered to the prostate by scanning ion beams in presence of intrafraction motion, as well as facilitates investigation of various motion interplay countermeasures.
Authors:
F Ammazzalorso; U Jelen
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Publication Detail:
Type:  Journal Article     Date:  2014-05-13
Journal Detail:
Title:  Physics in medicine and biology     Volume:  59     ISSN:  1361-6560     ISO Abbreviation:  Phys Med Biol     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  N91-9     Citation Subset:  IM    
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