Document Detail

A 4-year-old with pica, progressive incoordination, and decreased responsiveness.
MedLine Citation:
PMID:  10522333     Owner:  NLM     Status:  MEDLINE    
This article reports a typical case of subacute sclerosing panencephalitis (SSPE). The patient contracted measles as an infant during the 1989 to 1991 United States measles epidemic. At 4 1/2 years of age, he developed behavioral changes and quickly progressed through the typical clinical stages of SSPE. His EEG was characteristic. Serum and CSF measles immunoglobulin G were markedly elevated. He remains alive but is vegetative. To our knowledge, this is the first case of SSPE stemming from the 1989 to 1991 measles epidemic. Because infants--the group at highest risk to develop SSPE--were most severely affected by this measles outbreak, other cases of SSPE stemming from this epidemic may occur.
D J Dlugos; A R Brooks-Kayal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Seminars in pediatric neurology     Volume:  6     ISSN:  1071-9091     ISO Abbreviation:  Semin Pediatr Neurol     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-02-29     Completed Date:  2000-02-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9441351     Medline TA:  Semin Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  164-7     Citation Subset:  IM    
Children's Hospital of Philadelphia, PA 19104, USA.
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MeSH Terms
Brain / pathology
Child, Preschool
Chronic Disease
Disease Progression
Magnetic Resonance Imaging
Measles / complications
Movement Disorders / diagnosis*,  etiology
Persistent Vegetative State / diagnosis*,  etiology
Pica / diagnosis*,  etiology
Severity of Illness Index
Subacute Sclerosing Panencephalitis / complications,  diagnosis*,  virology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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