| The 3D vascular status of the follicle after HCG administration is qualitatively rather than quantitatively associated with its reproductive competence. | |
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MedLine Citation:
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PMID: 17179201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The objective of this study was to determine whether the vascular status of a single pre-ovulatory follicle is associated quantitatively and/or qualitatively with its reproductive competence. METHODS: We studied 61 monofollicular IVF-embryo transfer cycles. Just before single oocyte retrieval, follicle vascularization was detected by transvaginal power-Doppler, 3-dimensionally reconstructed, and analysed quantitatively by coloured/gray voxel ratio [vascularization index (VI)] and qualitatively by blood cell displacement [flow index (FI)] calculation. Cycles were sorted in two sets of two groups: low VI (<or=8%, n = 44) and high VI (>8%, n = 17); low FI (<or=30, n = 22) and high FI (>30, n = 39). RESULTS: Patients' characteristics, fertilization rates, and embryo morphology were comparable in all groups. In contrast, clinical pregnancy rates/oocyte retrieval (4% versus 33%, P < 0.009) and implantation rates (11% versus 50%, P < 0.04) were markedly poorer in the low as compared to the high FI groups, respectively, but remained similar between the low and the high VI groups (22% versus 23% and 38% versus 44%, respectively). CONCLUSIONS: A qualitative (FI) rather than quantitative (VI) relationship exists between vascular status and functional quality of the follicle after HCG administration. |
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Authors:
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Daniel H Mendez Lozano; Nelly Frydman; Jean M Levaillant; Stéphanie Fay; René Frydman; Renato Fanchin |
Publication Detail:
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Type: Journal Article Date: 2006-12-19 |
Journal Detail:
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Title: Human reproduction (Oxford, England) Volume: 22 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-04-02 Completed Date: 2007-07-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: England |
Other Details:
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Languages: eng Pagination: 1095-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology and Reproductive Medicine, INSERM Unit 782, Clamart, Université Paris XI, Le Kremlin-Bicêtre, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chorionic Gonadotropin / administration & dosage* Embryo Implantation Embryo Transfer Female Fertilization in Vitro Hormones / blood Humans Infertility, Female / therapy Oocytes / metabolism Ovary / metabolism Pregnancy Pregnancy Rate Prospective Studies Reproduction* |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 0/Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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