| 3D nongadolinium-enhanced ECG-gated MRA of the distal lower extremities: preliminary clinical experience. | |
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MedLine Citation:
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PMID: 18581339 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report our initial experience implementing a noncontrast-enhanced electrocardiograph (ECG) gated fast spin echo magnetic resonance angiography (MRA) technique for assessment of the calf arteries. MATERIALS AND METHODS: Noncontrast MRA images of 36 clinical patients examined over a 6-month period were evaluated by two radiologists for length and degree of stenosis of arterial segments. Diagnostic confidence in the technique was also recorded. The reference standard was a consensus reading by both radiologists using the noncontrast technique combined with two gadolinium-enhanced techniques: bolus-chase and time-resolved imaging. RESULTS: For stenosis evaluation the noncontrast technique demonstrated accuracy 79.4% (1083/1364), sensitivity 85.4% (437/512), and specificity 75.8% (646/852). The sequence demonstrated high negative predictive value (92.3%, 646/700). The technique had serious artifacts leading to poor diagnostic confidence in 17 patients (47.2%). These included motion (n = 7) and artifacts specific to the sequence, including inaccurate trigger delays (n = 5), linear artifact (n = 7), and vessel blurring (n = 5). When only patients in whom there was satisfactory diagnostic confidence were considered, accuracy, sensitivity, and negative predictive value were 92.2% (661/717), 92.4% (158/171), and 97.5% (503/516), respectively. CONCLUSION: Our results indicate that when technically successful, noncontrast-enhanced MRA using ECG-gated fast spin echo can provide accurate imaging of the calf and pedal arteries. However, further development and optimization are needed to improve the robustness of the technique. |
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Authors:
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Ruth P Lim; Elizabeth M Hecht; Jian Xu; James S Babb; Niels Oesingmann; Samson Wong; Bart E Muhs; Paul Gagne; Vivian S Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 28 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-07-10 Completed Date: 2008-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 181-9 Citation Subset: IM |
Copyright Information:
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(c) 2008 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology (MRI), New York University Medical Center, 560 First Avenue, New York, NY 10016, USA. limr02@med.nyu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Artifacts Constriction, Pathologic / diagnosis Electrocardiography* Female Humans Imaging, Three-Dimensional Leg / blood supply* Magnetic Resonance Angiography / methods* Male Middle Aged Motion Peripheral Vascular Diseases / diagnosis Predictive Value of Tests Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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