| 3D myocardial T(1) mapping at 3T using variable flip angle method: Pilot study. | |
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MedLine Citation:
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PMID: 23440632 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: Myocardial T(1) mapping is an emerging technique that could improve cardiovascular magnetic resonance diagnostic accuracy. In this study, a variable flip angle approach with B(1) correction is proposed at 3T on the myocardium, employing standard 3D spoiled fast gradient echo and echo planar imaging sequences. METHODS: The method was tested on phantoms to determine the set of standard 3D spoiled fast gradient echo angles adapted to myocardial T(1) measurements and was compared to the inversion-recovery spin-echo reference T(1) method. Seven volunteers underwent magnetic imaging resonance to acquire myocardial T(1) maps and T(1) values of the human heart. RESULTS: This original method demonstrated good reproducibility in phantoms and a significant correlation between variable flip angle T(1) values and reference inversion-recovery spin-echo T(1) values. It yielded myocardial T(1) values consistent with expected T(1) and an increasing homogenization of myocardial segments owing to B(1) correction. The mean myocardial T(1) value was 1341 ± 42 ms. CONCLUSION: Myocardial 3D T(1) mapping using the variable flip angle approach can potentially be useful for evaluating fibrosis on the entire myocardium using a standard clinical sequence. Magn Reson Med, 2013. © 2013 Wiley Periodicals, Inc. |
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Authors:
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Hélène Clique; Hai-Ling Margaret Cheng; Pierre-Yves Marie; Jacques Felblinger; Marine Beaumont |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-2-25 |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: - ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-2-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2013 Wiley Periodicals, Inc. |
Affiliation:
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Université de Lorraine, IADI, UMR S 947, Nancy, France; INSERM, IADI, U947, Nancy, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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