Document Detail

3D mesh based wall thickness measurement: identification of left ventricular hypertrophy phenotypes.
MedLine Citation:
PMID:  21096188     Owner:  NLM     Status:  MEDLINE    
Left ventricular hypertrophy (LVH) is a complex cardiac condition mainly identified by the thickening of the myocardial wall. Although most of the contemporary cardiac imaging modalities provide high resolution 3D images, the wall thickness (WT) is still measured within the acquired planes. This way of measurement may introduce an error as cardiac wall is not necessarily orthogonal to the plane. In this study we analyze how different approaches to measure WT can affect an automatic identification of hypertrophy. The compared approaches are: WT measured along surface normal and the one provided by a medial surface. For both approaches we evaluated their ability to identify LVH phenotypes by testing with two classifiers: Transductive Confidence Machine-k Nearest Neighbor (TCM-kNN) and Linear Discriminant Analysis (LDA). Fifty three subjects were included in this study: 18 patients with hypertrophic cardiomyopathy (HCM), 13 patients with hypertensive heart disease (HDD) and 22 sedentary subjects (CG). Medial surface based approach allowed obtaining higher classification accuracy in HDD patients, while normal based approach allowed for higher classification accuracy in HCM patients.
C Tobon-Gomez; C Butakoff; P Yushkevich; M Huguet; A F Frangi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2010     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-03-30     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2642-5     Citation Subset:  IM    
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MeSH Terms
Cardiomyopathy, Hypertrophic / physiopathology
Endocardium / pathology
Heart / physiopathology
Hypertrophy, Left Ventricular / diagnosis,  physiopathology*
Image Processing, Computer-Assisted / methods
Imaging, Three-Dimensional*
Models, Cardiovascular
Myocardial Contraction
Observer Variation
Pericardium / pathology
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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