Document Detail


The 34,XY(1),der(13) Chromosome Constitution with Loss of Y(2) Is Associated with Unilateral Testicular Hypoplasia in the Endangered Indian Blackbuck Antelope (Antilope cervicapra).
MedLine Citation:
PMID:  22846804     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The present study is the first report of unilateral testicular hypoplasia in 3 of 15 (20%) Indian blackbuck antelopes (Antilope cervicapra). Interestingly, the condition was restricted to only the right testis in all cases. Cytogenetic analysis revealed chromosomal aneuploidy in the affected individuals which had a 34,XY(1),der(13) karyotype with loss of the acrocentric (autosomal) Y(2) and an aberrant chromosome 13. We further determined that the semen output and the circulating testosterone levels were markedly low in the males with hypoplastic testes as compared to fertile males.
Authors:
S D Sontakke; L R Kandukuri; G Umapathy; K M Kulashekaran; P O Venkata; S Shivaji; L Singh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-25
Journal Detail:
Title:  Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation     Volume:  -     ISSN:  1661-5433     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316472     Medline TA:  Sex Dev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  240-246     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Affiliation:
Laboratory for the Conservation of Endangered Species Annexe I and Chromosome Diagnostics Facility, Clinical Research Facility-Medical Biotechnology Annexe II, Centre for Cellular and Molecular Biology (CSIR), Hyderabad, India.
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