Document Detail

3,4-Dihydroxyphenylacetic acid and homovanillic acid in serum and cerebrospinal fluid of psychotic patients estimated by a gas chromatographic method.
MedLine Citation:
PMID:  19604865     Owner:  NLM     Status:  In-Data-Review    
3,4-Dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) are extracted from 0.5 ml serum or cerebrospinal fluid (CSF) with ethyl acetate, reacted with pentafluoropropionic anhydride and hexafluoroisopropanol and separated on a 3% SE-30 gas chromatographic column. In the serum of 13 psychotic patients with paranoid-hallucinatory syndrome, mean values of 132 +/- 63 ng/ml DOPAC and 79 +/- 46 ng/ml HVA were found. The mean concentrations in CSF were 92 +/- 48 and 66 +/- 28 ng/ml respectively. The results indicate a high intraneuronal metabolism of dopamine; the ratio of DOPAC to HVA could give information about the extra- and intraneuronal uptake rates of this transmitter.
E S Markianos; E Rüther; H Gluba
Related Documents :
11403995 - Deprenyl stimulates the efflux of monoamines from the rat hypothalamus in vitro.
1707325 - Acute effects of intranigral application of mpp+ on nigral and bilateral striatal relea...
3008915 - Regional brain homovanillic acid following delta 9-tetrahydrocannabinol and cocaine.
1974665 - Physical and chemical considerations in the in vitro calibration of microdialysis probe...
16952435 - Innovative nanotechnologies for the delivery of oligonucleotides and sirna.
12947015 - Interleukin-13 upregulates vasodilatory 15-lipoxygenase eicosanoids in rabbit aorta.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroscience letters     Volume:  3     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1976 Sep 
Date Detail:
Created Date:  2009-07-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  37-40     Citation Subset:  -    
Psychiatrische Klinik der Universität München, 8 München 2 G.F.R.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Peripheral factors contributing to the volitional control of firing rates of the human motor units.
Next Document:  Quantitative studies of the brain specific antigens GFA, 14-3-2, synaptin C1, D1, D2, D3 and D5 in j...