Document Detail


3.0T whole-heart coronary magnetic resonance angiography performed with 32-channel cardiac coils: a single-center experience.
MedLine Citation:
PMID:  22887689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Whole-heart coronary magnetic resonance angiography (MRA) is a promising method for noninvasive, radiation-free detection and exclusion of obstructive coronary artery disease; however, the required imaging time and robustness of the technique are not yet satisfactory. We evaluated the value of whole-heart coronary MRA at 3.0T using a 32-channel cardiac coil, which reduces image-acquisition times and hence allows to increase the clinical throughput.
METHODS AND RESULTS: A total of 110 consecutive patients with suspected coronary artery disease referred for clinically indicated conventional coronary angiography were included in this prospective study. Acquisition of 3.0T coronary MRA data was done by using 32-channel receiver coils. An ECG-triggered, navigator-gated, inversion-recovery prepared, segmented gradient-echo sequence was used for image acquisition with an acceleration factor of 3 in the phase-encoding direction using generalized auto calibrating partially parallel acquisitions reconstruction. Acquisition of coronary MRA was successfully completed in 101 of 110 (92%) patients with average imaging time of 7.0±1.8 minutes. The sensitivity, specificity, positive and negative predictive value of coronary MRA on a patient-based analysis were 95.9% (47/49, 95% CI, 86.0%-99.4%), 86.5% (45/52, 95% CI, 74.2%-94.4%), 87.0% (47/54, 95% CI, 75.1%-94.6%) and 95.7% (45/47, 95% CI, 85.4%-99.4%), respectively.
CONCLUSIONS: Whole-heart coronary MRA at 3.0T using a 32-channel cardiac coil allows high overall accuracy for detecting significant coronary artery disease with reduced imaging time. It has potential to be a robust and alternative technique for ruling out significant coronary artery disease.
CLINICAL TRIAL REGISTRATION: URL: http://www.chictr.org. Unique identifier: ChiCTR-DDT-07000121.
Authors:
Qi Yang; Kuncheng Li; Xin Liu; Xiangying Du; Xiaoming Bi; Feng Huang; Renate Jerecic; Zhi Liu; Jing An; Dong Xu; Hairong Zheng; Zhaoyang Fan; Debiao Li
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-08-10
Journal Detail:
Title:  Circulation. Cardiovascular imaging     Volume:  5     ISSN:  1942-0080     ISO Abbreviation:  Circ Cardiovasc Imaging     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-19     Completed Date:  2012-11-23     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  101479935     Medline TA:  Circ Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  573-9     Citation Subset:  IM    
Affiliation:
Departments of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Cardiac-Gated Imaging Techniques / instrumentation*
China
Coronary Angiography
Coronary Stenosis / diagnosis*,  pathology,  radiography
Coronary Vessels / pathology*
Electrocardiography
Equipment Design
Female
Humans
Magnetic Resonance Angiography / instrumentation*
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Severity of Illness Index
Time Factors
Grant Support
ID/Acronym/Agency:
EB002623/EB/NIBIB NIH HHS; HL38698/HL/NHLBI NIH HHS; R01 EB002623/EB/NIBIB NIH HHS; R01 HL038698/HL/NHLBI NIH HHS
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