| 308-nm excimer lamp vs. 308-nm excimer laser for treating vitiligo: a randomized study. | |
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MedLine Citation:
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PMID: 20346025 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The 308-nm excimer laser and 308-nm excimer lamp have both been shown to be effective in treating vitiligo but a direct comparison has never been performed. OBJECTIVES: To test the equivalence of these two devices for treating nonsegmental vitiligo. PATIENTS AND METHODS: A randomized monocentric study was undertaken. One lesion was treated with the 308-nm excimer laser and its counterpart with the 308-nm excimer lamp. Lesions were treated twice weekly with the same dose on both sides for a total of 24 sessions. The evaluation was done by two independent physicians blinded to the treatment on direct light and ultraviolet light photos. RESULTS: Twenty patients were included: 17 completed the study and 104 lesions were treated. The two treatments showed similar results in terms of efficacy for a repigmentation of at least 50% (P = 0.006). The lamp induced more erythema than the laser. CONCLUSIONS: The 308-nm excimer lamp and laser showed a similar efficacy in treating vitiligo. For the same fluence, the lamp induced more erythema suggesting photobiological differences between the two devices. |
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Authors:
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F Le Duff; E Fontas; D Giacchero; L Sillard; J-P Lacour; J-P Ortonne; T Passeron |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial Date: 2010-03-23 |
Journal Detail:
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Title: The British journal of dermatology Volume: 163 ISSN: 1365-2133 ISO Abbreviation: Br. J. Dermatol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-21 Completed Date: 2010-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 188-92 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University Hospital of Nice, Rte de St-Antoine de Ginestiere, 06200 Nice, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Dose-Response Relationship, Radiation Female Humans Laser Therapy, Low-Level / methods* Lasers, Excimer / therapeutic use* Male Middle Aged Prospective Studies Single-Blind Method Treatment Outcome Ultraviolet Therapy / methods* Vitiligo / pathology, radiotherapy* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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