Document Detail


A 3-month preclinical trial to assess the performance of a new TVT-like mesh (TVTx) in a sheep model.
MedLine Citation:
PMID:  16628374     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to evaluate in a sheep model the performance of a new polypropylene mesh (TVTx), which is intended as a less invasive treatment for female stress urinary incontinence. Eight female sheep were used in this study, each one being implanted with eight TVTx samples. At each time-point (weeks 1, 2, 4, and 12) seven TVTx were pulled out, while one TVTx was carefully dissected for histological investigations. One TVTx and one TVT, moreover, were inserted and immediately pulled out for obtaining the initial pullout forces in all sheep. The initial pullout values of TVT and TVTx were overlapping. The pullout forces of TVTx were >5 N (500 g) and increasing from weeks 1 to 12 (p<0.001). Histology revealed good tissue integration of TVTx in the tissue within 12 weeks after implantation. No abnormal histological findings were observed. This data could support the realization of a clinical trial with the TVTx mesh.
Authors:
Masoumeh Rezapour; Giacomo Novara; Peter A Meier; Joerg Holste; Susanne Landgrebe; Walter Artibani
Related Documents :
10080314 - Analysis of a restored maxillary second premolar tooth by using three-dimensional finit...
18416414 - Evaluation of the cylinder implant thread height and width: a 3-dimensional finite elem...
7016944 - Determination of stress patterns in root-filled teeth incorporating various dowel designs.
10396694 - An in vitro study of implant--tooth-supported connections using a robot test system.
8654194 - Microdialysis sampling for hepatic metabolism studies. impact of microdialysis probe de...
6084654 - Cyclical phenomena occurring during the maturation of the enamel of rat incisor teeth. ...
Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2006-04-21
Journal Detail:
Title:  International urogynecology journal and pelvic floor dysfunction     Volume:  18     ISSN:  -     ISO Abbreviation:  Int Urogynecol J Pelvic Floor Dysfunct     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-12     Completed Date:  2007-04-04     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  9514583     Medline TA:  Int Urogynecol J Pelvic Floor Dysfunct     Country:  England    
Other Details:
Languages:  eng     Pagination:  183-7     Citation Subset:  IM    
Affiliation:
Department of Women's and Children's Health Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biocompatible Materials* / adverse effects
Female
Materials Testing
Models, Animal
Polypropylenes
Prosthesis Design
Sheep
Suburethral Slings* / adverse effects
Surgical Procedures, Minimally Invasive / adverse effects
Time Factors
Urinary Incontinence, Stress / surgery*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Polypropylenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Incidence of stress urinary incontinence among women in Turkey.
Next Document:  The effect of vaginal and cesarean delivery on lower urinary tract symptoms: what makes the differen...