| 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography for evaluation late after the mustard operation for transposition. | |
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MedLine Citation:
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PMID: 19930771 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Cardiovascular magnetic resonance assessment of adults late after an atrial redirection operation for transposition is demanding and time consuming. We hypothesised that the relatively fast and standardised 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography, or dynamic angiography, would be valuable in the periodic follow-up of these patients. METHODS: We investigated prospectively 36 adults with transposition using dynamic angiography, comparing our results against a comprehensive but non-contrast cardiovascular magnetic resonance protocol. We acquired 6 dynamic angiographic datasets after injection of contrast. The primary aim was to detect significant obstruction of the pathways for venous flow. RESULTS: In 4 patients (11%), we found evidence of moderate-to-severe, and thus clinically important, obstruction of systemic venous channels on standard cardiovascular magnetic resonance. All these patients were correctly identified by dynamic angiography. In 4 additional patients, we found mild and haemodynamically insignificant obstructions in the systemic venous channels. Of the 8 (22%) patients with any obstruction, 6 were detected by angiography. There were no false positives reported, giving sensitivity of 75% and specificity of 100%, a positive predictive value of 100%, and negative predictive value of 93%. In 1 patient, there was a moderate obstruction of the pulmonary venous compartment which was not readily seen by dynamic angiography. CONCLUSIONS: 3-dimensional dynamic angiography is a useful method for detecting anatomically moderate-to-severe, but not mild, obstructions in the systemic venous channels following Mustard repair for transposition. This technique can be used as a single imaging method and/or as complimentary to standard two dimensional cardiovascular magnetic resonance techniques for detection of clinically important obstructions in the systemic venous channels. |
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Authors:
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Bengt Johansson; Sonya V Babu-Narayan; Philip J Kilner; Timothy M Cannell; Raad H Mohiaddin |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-11-24 |
Journal Detail:
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Title: Cardiology in the young Volume: 20 ISSN: 1467-1107 ISO Abbreviation: Cardiol Young Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-30 Completed Date: 2010-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9200019 Medline TA: Cardiol Young Country: England |
Other Details:
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Languages: eng Pagination: 1-7 Citation Subset: IM |
Affiliation:
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Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cardiac Surgical Procedures / adverse effects*, methods Cohort Studies Constriction, Pathologic / diagnosis Contrast Media / diagnostic use Female Follow-Up Studies Humans Image Enhancement / methods* Imaging, Three-Dimensional / methods* Magnetic Resonance Angiography / methods* Postoperative Complications / diagnosis Predictive Value of Tests Pulmonary Veins Sensitivity and Specificity Transposition of Great Vessels / diagnosis, surgery* Vena Cava, Superior Venous Thrombosis / diagnosis*, etiology Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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//British Heart Foundation |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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