| 3 Tesla magnetic resonance imaging obtained 4 hours after intravenous gadolinium injection in patients with sudden deafness. | |
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MedLine Citation:
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PMID: 19958242 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONCLUSION: 3 Tesla (3T) magnetic resonance imaging (MRI) performed 4 h after intravenous gadolinium (Gd) injection provides sufficient anatomic resolution of the inner ear fluid spaces in sudden deafness. The signal intensity ratio (SIR) between the cochlea and cerebellum may be a good indicator of disruption of the blood-labyrinthine barrier. OBJECTIVES: We evaluated the inner ear 4 h after intravenous Gd injection to determine whether 3T MRI enables the acquisition of images of the affected inner ear in sudden deafness. METHODS: Ten patients underwent 3T MRI scanning 4 h after intravenous Gd injection. Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI was performed. RESULTS: The SIR varied from 0.45 to 2.17 in 11 affected ears and from 0.43 to 1.48 in 9 unaffected ears. The difference of contrast (affected ear vs unaffected ear) could be detected in five of the nine patients with unilateral sudden deafness. The Gd distribution was recognized in the vestibule of 10 affected ears and in the cochlea of 5 affected ears, in which no significant hydrops was observed. In the remaining vestibules and cochleas of affected ears, the Gd enhancement was too faint to evaluate the endolymphatic hydrops. |
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Authors:
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Mitsuhiko Tagaya; Masaaki Teranishi; Shinji Naganawa; Tomoyuki Iwata; Tadao Yoshida; Hironao Otake; Seiichi Nakata; Michihiko Sone; Tsutomu Nakashima |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 130 ISSN: 1651-2251 ISO Abbreviation: Acta Otolaryngol. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: England |
Other Details:
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Languages: eng Pagination: 665-9 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Nagoya University, Graduate School of Medicine, Nagoya, Japan. mi-man@ra2.so-net.ne.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Audiometry, Pure-Tone Auditory Threshold / physiology Cerebellum / pathology Cochlea / pathology* Contrast Media* Endolymph / physiology Endolymphatic Hydrops / diagnosis, pathology Female Follow-Up Studies Hearing Loss, Sudden / diagnosis*, pathology Heterocyclic Compounds / diagnostic use* Humans Image Enhancement* Image Processing, Computer-Assisted* Imaging, Three-Dimensional* Injections, Intravenous Magnetic Resonance Imaging* Male Middle Aged Organometallic Compounds / diagnostic use* Perilymph / physiology Sensitivity and Specificity Vestibule, Labyrinth / pathology |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Heterocyclic Compounds; 0/Organometallic Compounds; 112188-16-6/gadoteridol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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