| 3-T high-b-value diffusion-weighted MR imaging of hyperacute ischemic stroke in the vertebrobasilar territory. | |
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MedLine Citation:
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PMID: 22178021 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Diffusion-weighted imaging (DWI) is the key method for diagnosing acute ischemic stroke. Applied b values in stroke diffusion studies are usually in the range of 800-1500s/mm(2), but progress in magnetic resonance (MR) technology now permits higher b values. However, it is uncertain whether high-b-value DW sequences improve the detection of acute and hyperacute ischemic lesions. The aim of this study is to explore the sensitivity of high b values vs standard b values at 3T in hyperacute stroke in the vertebrobasilar territory. MATERIAL AND METHODS: 3-T DWI was performed in referred patients with a clinical diagnosis of hyperacute (<6h from onset) cerebral infarction using conventional MR sequences as well as DW sequences. Examinations included the usual DW sequence (b=1000s/mm(2)) and two high-b-value DW sequences (b=3000s/mm(2) and b=5000s/mm(2)). Patients with hyperacute stroke in the posterior circulation were included if MR imaging, including the usual DW sequence, was normal or if the diagnosis was uncertain. RESULTS: In all six studied patients, ischemic lesions were better visualized with high-b-value DWI compared with the usual DWI. On increasing the b value, DW images appeared to be noisier while white-matter tracts became progressively hyperintense. CONCLUSION: At 3T, high-b-value DW sequences may be helpful for diagnosing hyperacute infarctions in the vertebrobasilar territory, but further studies are needed to confirm this hypothesis. |
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Authors:
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Michael Lettau; Mona Laible |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-16 |
Journal Detail:
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Title: Journal of neuroradiology. Journal de neuroradiologie Volume: - ISSN: 0150-9861 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705086 Medline TA: J Neuroradiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Division of Neuroradiology, Department of Neurosurgery, University of Freiburg Medical Center, Breisacher Str. 64, D-79106 Freiburg, Germany. |
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