Document Detail

3-T contrast-enhanced MR angiography in evaluation of suspected intracranial aneurysm: comparison with MDCT angiography.
MedLine Citation:
PMID:  18212224     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to prospectively evaluate a high-spatial-resolution contrast-enhanced 3-T MR angiography protocol for detection and characterization of intracranial aneurysms and to compare the results with those of MDCT angiography. SUBJECTS AND METHODS: Forty-one patients with suspected intracranial aneurysm underwent high-spatial-resolution 3D contrast-enhanced MR angiography and CT angiography (CTA). With a generalized autocalibrating partially parallel acquisition algorithm with an acceleration factor of 4 at 3 T, contrast-enhanced MR angiographic images were acquired over 20 seconds with a spatial-resolution of 0.7 x 0.7 x 0.8 mm. CTA images were acquired with a spatial resolution of 0.35 x 0.35 x 0.8 mm on a 16-MDCT scanner in 17 seconds. The images from the two studies were evaluated independently by two neuroradiologists for image quality, presence of aneurysm, and characterization of aneurysm. The dimensions of the aneurysm were measured independently with both techniques. RESULTS: A total of 25 aneurysms were identified with both contrast-enhanced MR angiography and CTA. A comparative analysis of detection and depiction of aneurysms showed excellent interobserver agreement for both contrast-enhanced MR angiography (kappa = 0.81) and CTA (kappa = 0.91) images. There was significant correlation between the techniques for both qualitative assessment of aneurysm depiction (rho = 0.92; 95% CI, 0.88-0.95) and quantitative dimensional measurement of aneurysm size (r = 0.94; 95% CI, 0.92-0.97). CONCLUSION: Contrast-enhanced MR angiography at 3 T is reliable for evaluation and characterization of intracranial aneurysms. The results are comparable with those of MDCTA.
Kambiz Nael; J Pablo Villablanca; Léonard Mossaz; Whitney Pope; Alex Juncosa; Gerhard Laub; J Paul Finn
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  190     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-23     Completed Date:  2008-02-11     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  389-95     Citation Subset:  AIM; IM    
Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, 10945 Le Conte Ave., Suite 3371, Los Angeles, CA 90095-7206, USA.
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MeSH Terms
Cerebral Angiography / methods*
Gadolinium DTPA / diagnostic use*
Intracranial Aneurysm / diagnosis*
Magnetic Resonance Angiography / methods*
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
80529-93-7/Gadolinium DTPA

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