Document Detail


3-T MRI detects inflammatory stenosis of the vertebral artery in giant cell arteritis.
MedLine Citation:
PMID:  18172573     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Giant cell arteritis (GCA) is a granulomatous vasculitis. Early diagnosis is important for the initiation of corticosteroid treatment because the arteritis can result in blindness. In most of the cases, the superficial cranial arteries are affected. However, extracranial involvement of various arteries is known. Here, we report a case of histologically proven GCA with an inflammatory stenosis of the right vertebral artery. For complete evaluation of the extension of the disease, an optimized protocol of high-resolution magnetic resonance imaging at 3 T in combination with contrast-enhanced magnetic resonance angiography was performed. This non-invasive method facilitates the differentiation of inflamed and healthy segments of small cranial arteries, may help to find appropriate sites for biopsy, and allows the assessment of affected extracranial vessels. In this patient case, even the cause of vertebral stenosis--inflammatory versus arteriosclerotic--could be elucidated.
Authors:
J Geiger; M Uhl; H H Peter; M Langer; T A Bley
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-01-03
Journal Detail:
Title:  Clinical rheumatology     Volume:  27     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-03     Completed Date:  2008-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  663-6     Citation Subset:  IM    
Affiliation:
Department of Radiology, University of Freiburg, Freiburg, Germany. julia.geiger@uniklinik-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Aged, 80 and over
Female
Giant Cell Arteritis / complications,  pathology*
Humans
Magnetic Resonance Imaging
Vertebral Artery / pathology*
Vertebrobasilar Insufficiency / etiology*

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