| 3-D imaging of the CNS. | |
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MedLine Citation:
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PMID: 2259430 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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3-D gradient echo techniques, and in particular FLASH, represent a significant advance in MR imaging strategy allowing thin section, high resolution imaging through a large region of interest. Anatomical areas of application include the brain, spine, and extremities, although the majority of work to date has been performed in the brain. Superior T1 contrast and thus sensitivity to the presence of GdDTPA is achieved with 3-D FLASH when compared to 2-D spin echo technique. There is marked arterial and venous enhancement following Gd DTPA administration on 3-D FLASH, a less common finding with 2-D spin echo. Enhancement of the falx and tentorium is also more prominent. From a single data acquisition, requiring less than 11 min of scan time, high resolution reformatted sagittal, coronal, and axial images can obtained in addition to sections in any arbitrary plane. Tissue segmentation techniques can be applied and lesions displayed in three dimensions. These results may lead to the replacement of 2-D spin echo with 3-D FLASH for high resolution T1-weighted MR imaging of the CNS, particularly in the study of mass lesions and structural anomalies. The application of similar T2-weighted gradient echo techniques may follow, however the signal-to-noise ratio which can be achieved remains a potential limitation. |
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Authors:
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V M Runge; D Y Gelblum; M L Wood |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neuroradiology Volume: 32 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 1990 |
Date Detail:
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Created Date: 1991-01-31 Completed Date: 1991-01-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: GERMANY |
Other Details:
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Languages: eng Pagination: 356-66 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Kentucky Medical Center, Lexington. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology* Brain Diseases / diagnosis* Brain Neoplasms / diagnosis Contrast Media Gadolinium DTPA Humans Image Processing, Computer-Assisted* Magnetic Resonance Imaging* / methods Male Middle Aged Organometallic Compounds / diagnostic use Pentetic Acid / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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