| 2'5'-Oligoadenylate polymerase activity in the rat small intestine. | |
| | |
MedLine Citation:
|
PMID: 7173529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
2'5'-Oligoadenylates are potent protein synthesis inhibitors: they are synthesized by a polymerase which was first described in interferon-treated cells. This system may also be involved in a normal process of cell proliferation and differentiation, in the absence of any viral infection. The small intestine enterocyte has been investigated as a model to test this hypothesis. The presence of 2'5'-oligoadenylate polymerase activity is demonstrated in the intestinal mucosa of normal adult rats. The distribution of this enzyme, and of the enzymes degrading 2'5' oligoadenylates have been investigated on enterocyte pools selectively extracted, under mild conditions, from the different parts of the rat small intestine. Similar results were obtained with enterocytes extracted from the mucosa of germ-free animals. |
| | |
Authors:
|
J Marti; P Fournie; J Lafont |
Related Documents
:
|
19276679 - The herbal extract, iberogast, improves jejunal integrity in rats with 5-fluorouracil (... 3096849 - Dietary influences on rat hepatic and intestinal dt-diaphorase activity. 18820869 - Oxymatrine attenuates intestinal ischemia/reperfusion injury in rats. 6764709 - The effects of mecholyl and atropine on the muscarinic receptors in rat small intestine... 3837859 - Antidipsogenic action of vasoactive intestinal peptide in the rat. 8173009 - Prostaglandin e2 accelerates enzymatic and morphological maturation of the small intest... 6226909 - Studies on diabetic cataract in rats induced by streptozotocin. ii. biochemical examina... 16741049 - Alterations of gene expressions of preproet-1 and et receptors in brains of endotoxemic... 9717449 - Hepatoprotective activity of trichopus zeylanicus extract against paracetamol-induced h... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Differentiation; research in biological diversity Volume: 22 ISSN: 0301-4681 ISO Abbreviation: Differentiation Publication Date: 1982 |
Date Detail:
|
Created Date: 1983-02-25 Completed Date: 1983-02-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0401650 Medline TA: Differentiation Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 201-4 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
2',5'-Oligoadenylate Synthetase
/
metabolism* Alkaline Phosphatase / metabolism Animals Chromatography, High Pressure Liquid Intestine, Small / enzymology* Kinetics Male Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
|
EC 2.7.7.-/2',5'-Oligoadenylate Synthetase; EC 3.1.3.1/Alkaline Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vimentin in the central nervous system. A study of the mesenchymal-type intermediate filament-protei...
Next Document: A reproducible colonial morphology formed by individual pluripotent embryonal carcinoma cells in cul...