Document Detail

24-hr blood pressure in HDT-bed rest and short-lasting space flight.
MedLine Citation:
PMID:  18372694     Owner:  NLM     Status:  MEDLINE    
In 2 ESA-cosmonauts we compared the 24-hr profiles in blood pressure (BP) and heart rate (HR) to those that we had observed in an earlier head-down tilted (HDT) bed rest study. In view of the lack of gravitational stress, an attenuated profile was expected, as in HDT. To obtain a full profile we measured automatic upper-arm cuff measurements in 2 cosmonauts, combined with PortapresTM recordings in one. Unlike HDT, actual microgravity did not result in attenuated circadian profiles. The levels of systolic and diastolic pressures tended to be slightly lower in flight. Only nighttime heart rate was significantly lower in Space.
John M Karemaker; Janneke Gisolf; Wim J Stok; Gert A van Montfrans
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology     Volume:  14     ISSN:  1077-9248     ISO Abbreviation:  J Gravit Physiol     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2008-03-31     Completed Date:  2008-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9437868     Medline TA:  J Gravit Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  P49-50     Citation Subset:  IM    
Academic Medical Center, University ofAmsterdam, Department of Systems Physiology, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.
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MeSH Terms
Bed Rest*
Blood Pressure*
Blood Pressure Monitoring, Ambulatory
Cardiac Output
Cardiovascular System / physiopathology*
Circadian Rhythm*
Head-Down Tilt*
Heart Rate
Space Flight*
Stroke Volume
Vascular Resistance
Weightlessness Simulation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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