| 24-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine. | |
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MedLine Citation:
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PMID: 12505396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Baseline and perianaesthetic 24-hour Holter recordings were carried out in six healthy beagles. After dexmedetomidine premedication anaesthesia was induced with propofol and maintained with propofol infusion or isoflurane for one hour. Dexmedetomidine alone was used as control. The recordings were analysed for ventricular premature complexes (VPC), atrioventricular (AV) blocks and mean heart rate/hour (HR). In most recordings, no ventricular arrhythmias were detected, the maximum frequency being two VPCs/24 h. VPCs were not seen during anaesthesia or during the recovery period. The development of second-degree AV-blocks varied from dog to dog. Most of the heart blocks were seen during the premedication period when bradycardia was most prominent. During the subsequent night, HR was similar between treatments and did not differ from that seen on the baseline recordings. In beagles treated with dexmedetomidine alone or combined with propofol or propofol/isoflurane, ventricular arrhythmias were not detected more frequently than those reported in healthy non-anaesthetised dogs. |
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Authors:
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E Kuusela; M Raekallio; H Hietanen; J Huttula; O Vainio |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Veterinary journal (London, England : 1997) Volume: 164 ISSN: 1090-0233 ISO Abbreviation: Vet. J. Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-12-30 Completed Date: 2003-05-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9706281 Medline TA: Vet J Country: England |
Other Details:
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Languages: eng Pagination: 235-9 Citation Subset: IM |
Copyright Information:
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Copyright 2002 Published by Elsevier Science Ltd. |
Affiliation:
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Faculty of Veterinary Medicine, Department of Clinical Veterinary Sciences, Helsinki University, PO Box 57, FIN-00014, Helsinki, Finland. erja.kuusela@helsinki.fi |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, General
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veterinary Anesthetics, Inhalation / adverse effects Anesthetics, Intravenous / adverse effects Animals Arrhythmias, Cardiac / chemically induced* Dexmedetomidine / administration & dosage, adverse effects* Dogs Drug Interactions Drug Monitoring* Female Heart Rate / drug effects* Hypnotics and Sedatives / administration & dosage, adverse effects Isoflurane / administration & dosage, adverse effects Male Preanesthetic Medication / adverse effects*, veterinary* Propofol / administration & dosage, adverse effects Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 0/Hypnotics and Sedatives; 113775-47-6/Dexmedetomidine; 2078-54-8/Propofol; 26675-46-7/Isoflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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