| 2308 second trimester terminations using extra-amniotic or intra-amniotic prostaglandin E2: an analysis of efficacy and complications. | |
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MedLine Citation:
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PMID: 2620054 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 2308 mid-trimester terminations using PGE2 extra-amniotically (1608) or intra-amniotically (700) has been analysed for efficacy and immediate and early morbidity. The mean induction-to-abortion intervals were similar for the two routes. Overall, 67% of the patients were in hospital for 1 night. Morbidity rates were similar for the two administration routes and were no higher than those reported for second trimester terminations using dilatation and evacuation. Minor side-effects of vomiting occurred in 1006 (44%) and diarrhoea in 320 (14%). Forty (1.7%) lost more than 500 ml of blood during termination and 13 (0.6%) were transfused. Major complications were extremely rare and genital tract trauma only occurred in 4 (0.17%) and proven pelvic infection in 2 (0.08%) patients. Thirty-three (1.4%) were readmitted and required a surgical evacuation of the uterus. Since long-term complications have been assessed for this method of termination and found to be infrequent, we see no reason to consider a change in methods for second trimester terminations. |
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Authors:
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N C Hill; I Z MacKenzie |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of obstetrics and gynaecology Volume: 96 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1989 Dec |
Date Detail:
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Created Date: 1990-03-21 Completed Date: 1990-03-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1424-31 Citation Subset: AIM; IM; J |
Affiliation:
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Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced* Adolescent Adult Dinoprostone / administration & dosage*, adverse effects Dose-Response Relationship, Drug Female Fever / etiology Genitalia, Female / injuries Humans Infection / etiology Length of Stay Patient Readmission Postpartum Hemorrhage / etiology Pregnancy Pregnancy Trimester, Second Time Factors Vomiting / etiology |
| Chemical | |
Reg. No./Substance:
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363-24-6/Dinoprostone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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