Document Detail

2,3-Bisphosphoglycerate, fructose, 2,6-bisphosphate and glucose 1,6-bisphosphate during maturation of reticulocytes with low 2,3-bisphosphoglycerate content.
MedLine Citation:
PMID:  2177836     Owner:  NLM     Status:  MEDLINE    
In contrast to the species with erythrocytes of high 2,3-bisphosphoglycerate content, in the sheep the concentration of 2,3-bisphosphoglycerate decreases during maturation of reticulocytes. The decrease can be explained by the drop of the phosphofructokinase/pyruvate kinase and 2,3-bisphosphoglycerate synthase/2,3-bisphosphoglycerate phosphatase activity ratios that result from the decline of phosphofructokinase, pyruvate kinase, phosphoglycerate mutase and the bifunctional enzyme 2,3-bisphosphoglycerate synthase/phosphatase. The concentrations of fructose 2,6-bisphosphate and aldohexose 1,6-bisphosphates also decrease during sheep reticulocyte maturation in parallel to the 6-phosphofructo 2-kinase and the glucose 1,6-bisphosphate synthase activities.
C Gallego; J Carreras
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular and cellular biochemistry     Volume:  99     ISSN:  0300-8177     ISO Abbreviation:  Mol. Cell. Biochem.     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1991-03-08     Completed Date:  1991-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364456     Medline TA:  Mol Cell Biochem     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  21-4     Citation Subset:  IM    
Departament de Ciències Fisiològiques Humanes i de la Nutrició, Facultat de Medicina, Universitat de Barcelona, Spain.
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MeSH Terms
Bisphosphoglycerate Mutase / blood
Diphosphoglyceric Acids / blood*
Fructosediphosphates / blood*
Glucose-6-Phosphate* / analogs & derivatives*
Glucosephosphates / blood*
Multienzyme Complexes
Phosphofructokinase-1 / blood
Phosphoric Monoester Hydrolases / blood
Pyruvate Kinase / blood
Reticulocytes / metabolism*
Reg. No./Substance:
0/Diphosphoglyceric Acids; 0/Fructosediphosphates; 0/Glucosephosphates; 0/Multienzyme Complexes; 0/glucose-1,6-bisphosphate; 138-81-8/2,3-Diphosphoglycerate; 56-73-5/Glucose-6-Phosphate; 79082-92-1/fructose 2,6-diphosphate; EC; EC Kinase; EC 3.1.3.-/Phosphoric Monoester Hydrolases; EC phosphatase; EC Mutase

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