| (2-Nitrophenyl)acetyl: a new, selectively removable hydroxyl protecting group. | |
| | |
MedLine Citation:
|
PMID: 20361745 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
|
The utility of the (2-nitrophenyl)acetyl (NPAc) group for the protection of hydroxyl functions is reported. (2-Nitrophenyl)acetates are readily prepared starting from the commercially available, inexpensive (2-nitrophenyl)acetic acid, and these esters are stable under a series of common carbohydrate transformations. The NPAc group can be removed selectively using Zn and NH(4)Cl without affecting a series of common protecting groups. This new protecting group is orthogonal with the commonly used tert-butyldimethylsilyl, levulinoyl, 9-fluorenylmethoxycarbonyl, naphthylmethyl, and p-methoxybenzyl groups. |
| | |
Authors:
|
Katalin Daragics; Péter Fügedi |
Related Documents
:
|
7474005 - Primary repair of colon injuries: a prospective randomized study. 3993845 - Cecoproctostomy. 7695115 - Colonization of mechanical ventilation bags during use. 18680195 - Budesonide induction and maintenance therapy for crohn's disease during pregnancy. 16336335 - Long-term follow-up study to evaluate the efficacy and safety of the doxazosin gastroin... 7924705 - Evaluation of anemia caused by hemorrhoidal bleeding. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Organic letters Volume: 12 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-04-30 Completed Date: 2010-08-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
|
Languages: eng Pagination: 2076-9 Citation Subset: - |
Affiliation:
|
Department of Carbohydrate Chemistry, Chemical Research Center, Hungarian Academy of Sciences, H-1025 Budapest, Hungary. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: One-Pot Synthesis of Substituted Di-Hydrofurans from Lewis Base-Catalyzed Three-Component Condensati...
Next Document: Radical Amination with Trimethylstannylated Benzophenone Imine.