Document Detail


1H and 13C NMR assignments of all three isomeric o-fluoronaphthaldehydes and three o-fluorophenanthrene aldehydes.
MedLine Citation:
PMID:  19810003     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three isomeric o-fluoronaphthaldehydes, 9-fluorophenanthrene, and three previously unreported o-fluorophenanthrene aldehydes were analyzed in detail by multiple NMR techniques to provide unambiguous assignment of structures and resonances. The six aldehydes serve as the key starting materials for novel chiral ligands used in highly enantioselective rhodium-catalyzed asymmetric hydrogenation reactions.
Authors:
Carl A Busacca; Scot Campbell; Nina C Gonnella; Chris H Senanayake
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Magnetic resonance in chemistry : MRC     Volume:  48     ISSN:  1097-458X     ISO Abbreviation:  Magn Reson Chem     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9882600     Medline TA:  Magn Reson Chem     Country:  England    
Other Details:
Languages:  eng     Pagination:  74-9     Citation Subset:  IM    
Copyright Information:
Copyright 2009 John Wiley & Sons, Ltd.
Affiliation:
Department of Chemical Development, Boehringer-Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA. carl.busacca@boehringer-ingelheim.com
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MeSH Terms
Descriptor/Qualifier:
Aldehydes / chemistry*
Carbon Isotopes
Fluorine / chemistry*
Hydrogen
Isomerism
Ligands
Magnetic Resonance Spectroscopy
Molecular Structure
Naphthalenes / chemistry*
Phenanthrenes / chemistry*
Chemical
Reg. No./Substance:
0/1-fluoronaphthaldehyde; 0/Aldehydes; 0/Carbon Isotopes; 0/Ligands; 0/Naphthalenes; 0/Phenanthrenes; 1333-74-0/Hydrogen; 66-77-3/1-naphthaldehyde; 7782-41-4/Fluorine; 85-01-8/phenanthrene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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