| 1997 Sir William Refshauge Lecture. Skeletal muscle glucose metabolism during exercise: implications for health and performance. | |
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MedLine Citation:
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PMID: 9923727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Skeletal muscle glucose uptake and metabolism are major determinants of whole body glucose metabolism in response to exercise and insulin stimulation. An understanding of the mechanisms responsible for increased muscle glucose uptake under these conditions is crucial for identifying strategies that enhance insulin action and exercise performance. Regular exercise, by favourably influencing the intramuscular determinants of glucose uptake, enhances insulin action. For this reason, it is recommended in the prevention and management of disease states that are characterised by insulin resistance ("metabolic syndrome"). Increased skeletal muscle glucose uptake, as a consequence of carbohydrate ingestion, maintains carbohydrate supply to contracting muscle, at a time when glycogen levels are reduced, and is associated with enhanced performance. Thus, both health and exercise performance are influenced by the metabolism of glucose within skeletal muscle. |
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Authors:
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M Hargreaves |
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Publication Detail:
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Type: Lectures; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of science and medicine in sport / Sports Medicine Australia Volume: 1 ISSN: 1440-2440 ISO Abbreviation: J Sci Med Sport Publication Date: 1998 Dec |
Date Detail:
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Created Date: 1999-03-25 Completed Date: 1999-03-25 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9812598 Medline TA: J Sci Med Sport Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 195-202 Citation Subset: IM; S |
Affiliation:
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School of Health Sciences, Deakin University, Burwood, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dietary Carbohydrates
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administration & dosage,
metabolism Exercise / physiology* Exercise Therapy Glucose / metabolism* Glycogen / metabolism Health* Humans Insulin / metabolism, physiology Insulin Resistance / physiology Muscle Contraction / physiology Muscle, Skeletal / metabolism* Physical Exertion / physiology |
| Chemical | |
Reg. No./Substance:
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0/Dietary Carbohydrates; 11061-68-0/Insulin; 50-99-7/Glucose; 9005-79-2/Glycogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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