| (18)F-FDG-PET/CT predicts survival in hypopharyngeal squamous cell carcinoma. | |
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MedLine Citation:
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PMID: 23337965 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: We investigated the relationship between overall survival of patients and pretreatment [(18)F]-2-fluorodeoxyglucose ((18)F-FDG) uptake, assessed by positron emission tomography combined with computed tomography (PET/CT) in hypopharyngeal squamous cell carcinoma. METHODS: Thirty-one patients who were newly diagnosed as resectable hypopharyngeal squamous cell carcinoma underwent pretreatment (18)F-FDG-PET/CT. We used the maximum standardized uptake value (SUVmax) as (18)F-FDG uptake. Overall survival rate was calculated by the Kaplan-Meier method. RESULTS: The median SUVmax was 11.53 (range 2.49-22.33). Patients with SUVmax ≥ 13 significantly exhibited shorter overall survival in univariate analysis (p < 0.01). Moreover, by Cox proportional hazards model of multivariate analysis, SUVmax ≥ 13 was a significant prognostic factor independent of clinical T and N classification, and treatment group (p < 0.02). CONCLUSIONS: These results suggested that SUVmax obtained by pretreatment (18)F-FDG PET/CT assessment is an important prognostic factor in patients with hypopharyngeal squamous cell carcinoma. |
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Authors:
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Hidenori Suzuki; Katsuhiko Kato; Yasushi Fujimoto; Yoshiyuki Itoh; Mariko Hiramatsu; Takashi Maruo; Shinji Naganawa; Yasuhisa Hasegawa; Tsutomu Nakashima |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-22 |
Journal Detail:
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Title: Annals of nuclear medicine Volume: - ISSN: 1864-6433 ISO Abbreviation: Ann Nucl Med Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8913398 Medline TA: Ann Nucl Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Head and Neck Surgery, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan, hi.suzuki@aichi-cc.jp. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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