Document Detail

The 125I-Hippuran renogram in rabbit kidneys after graded warm ischaemia.
MedLine Citation:
PMID:  7375848     Owner:  NLM     Status:  MEDLINE    
125I-Hippuran renography was performed after temporary renal arterial clamping in contralateral nephrectomized rabbits. Mean renograms for the experimenttal groups were calculated for 0, 1, 1 1/2, 2, 2 1/2 and 3 h of warm ischaemia. The appearance phase, the 1 min uptake phase and excretion ratio were evaluated. The kidney function was monitored by serum-creatinine. Warm ischaemia of 1, 1 1/2 and 2 h resulted in a late maximum peak and delayed excretion, and for the last group in an accumulation curve. The uptake capacity was normal for these groups. Protracted ischaemia of 2 1/2 and 3 h affected also the appearance and uptake phase resulting in a slower and decreased Hippuran uptake of 50% and 34% respectively. Duration of warm ischaemia and changes in the renogram were well correlated. A normal uptake phase predicts restitution of the kidney function and 100% survival.
J I Dahlager; T Bilde
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  14     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1980  
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  85-90     Citation Subset:  IM    
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MeSH Terms
Creatinine / blood
Hot Temperature
Iodine Radioisotopes / diagnostic use*
Iodohippuric Acid / diagnostic use*
Ischemia* / etiology
Kidney / blood supply*,  physiopathology
Kidney Diseases / diagnosis*
Radioisotope Renography*
Renal Artery
Time Factors
Reg. No./Substance:
0/Iodine Radioisotopes; 147-58-0/Iodohippuric Acid; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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