| Eleven-year study of causes of neonatal bacterial meningitis in Ahvaz, Iran. | |
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MedLine Citation:
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PMID: 20202151 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Bacterial meningitis is a devastating infection with a high mortality rate, especially in neonates. The aim of this study was to determine the causative agents that cause bacterial meningitis in Khuzestan province in the south-western region of Iran. METHODS: A descriptive, cross-sectional study was carried out from 1997 to 2007 at the neonatal ward of a university teaching hospital (Emam Khomeini hospital) in Ahvaz. All infants younger than 29 days old who suffered from meningitis were included. Laboratory tests included Gram stain, culture, and biochemical tests. Cases were defined as meningitis if the cerebrospinal fluid culture was positive. RESULTS: Based on cerebrospinal fluid culture, 31 infants were identified as having bacterial meningitis. Eleven (35.5%) of these cases were caused by Klebsiella pneumoniae, nine (29%) were caused by Enterobacter spp., three (9.6%) were caused by Escherichia coli, three (9.6%) were caused by Enterococcus spp., two (6.4%) were caused by Acinetobacter, and one case each (3.2%) was caused by Staphylococcus aureus, Pseudomonas aeruginosa and nontypeable Haemophilus influenzae. The male-to-female ratio was 2 : 1 (67.7% were male). The birthweights of 20 (64.5%) patients were under 2500 g and 11 (35.4%) patients had normal birthweights. Thirteen (42%) were early-onset cases and 18 (58%) were late-onset cases. More than half of the cases (54.8%) acquired the infection from the hospital. Blood cultures were positive for 18 (58%) patients. Thirty-two percent of cases died in spite of treatment. CONCLUSIONS: Klebsiella pneumoniae and Enterobacter spp. were the two main causative agents that caused neonatal bacterial meningitis, and nosocomial meningitis was the most common type in our ward. |
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Authors:
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Mohammad Hasan Aletayeb; Farajzadeh Sheikh Ahmad; Dehdashtian Masood |
Publication Detail:
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Type: Journal Article Date: 2010-02-26 |
Journal Detail:
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Title: Pediatrics international : official journal of the Japan Pediatric Society Volume: 52 ISSN: 1442-200X ISO Abbreviation: Pediatr Int Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-20 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100886002 Medline TA: Pediatr Int Country: Australia |
Other Details:
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Languages: eng Pagination: 463-6 Citation Subset: IM |
Affiliation:
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Neonatology Division, Emam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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therapeutic use Cross Infection / drug therapy, epidemiology*, microbiology Cross-Sectional Studies Enterobacteriaceae Infections / diagnosis, drug therapy, epidemiology* Female Follow-Up Studies Hospitals, University Humans Incidence Infant, Newborn Intensive Care Units, Neonatal Iran / epidemiology Klebsiella Infections / diagnosis, drug therapy, epidemiology* Male Meningitis, Bacterial / cerebrospinal fluid, drug therapy, epidemiology*, microbiology Risk Assessment Survival Rate Time Factors Treatment Outcome Urban Population |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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