Document Detail


10-year survival rate in 92 patients with invasive bladder carcinoma treated by bladder sparing methods.
MedLine Citation:
PMID:  9366149     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The 10-year survival rate was evaluated in 92 patients with invasive bladder cancer (stages T 2 to 4) who were treated between 1966 and 1985 using bladder-sparing methods such as intravesical instillation of antineoplastic agents, transurethral resection, partial cystectomy, arterial infusion chemotherapy, radiation and embolization of the internal iliac artery. The overall 5-year and 10-year survival rates were 68.1% and 53.9% respectively at a median follow-up period of 60 months. The 10-year survival rate for patients with clinical stage T 2, T3a, T3b and T 4 were 83.7%, 58.9%, 50.8% and 0%, respectively. Our data were comparable or superior to those following radical cystectomy combined with pre- and post-operative radiation or chemotherapy. In conclusion, our bladder-sparing conservative method is thought to be an alternative treatment for advanced bladder cancer and provides a favorable survival rate as well as an improved quality of life with preservation of bladder function.
Authors:
H Ogawa; T Nishimura; N Hori; H Abe; H Ito; M Kubota; I Kiriyama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nihon Ika Daigaku zasshi     Volume:  64     ISSN:  0048-0444     ISO Abbreviation:  Nippon Ika Daigaku Zasshi     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1998-01-21     Completed Date:  1998-01-21     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  7505726     Medline TA:  Nihon Ika Daigaku Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  446-54     Citation Subset:  IM    
Affiliation:
Department of Urology, Kanto Teishin Hospital, Japan.
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MeSH Terms
Descriptor/Qualifier:
Administration, Intravesical
Adult
Aged
Aged, 80 and over
Antineoplastic Agents / administration & dosage
Carcinoma, Transitional Cell / mortality,  pathology,  therapy*
Combined Modality Therapy
Cystectomy
Embolization, Therapeutic
Female
Follow-Up Studies
Humans
Infusions, Intra-Arterial
Male
Middle Aged
Survival Rate
Time Factors
Treatment Outcome
Urinary Bladder Neoplasms / mortality,  pathology,  therapy*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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