| 1-year results after posterior lamellar keratoplasty with manually dissected donor tissue | |
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MedLine Citation:
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PMID: 20560099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Posterior lamellar keratoplasty (PLK) is a reasonable alternative to penetrating keratoplasty (PK) for pathological changes of the corneal endothelium. The lamellar preparation of the donor tissue can be done in an automated fashion with a microkeratome, Descemet Stripping Automated Keratoplasty (DSAEK) or manually, Descemet Stripping Endothelial Keratoplasty (DSEK). Here, we describe our clinical results with one year follow-up using manually dissected donor lamellae for PLK. METHODS: For 28 eyes (28 patients) best-corrected visual acuity, corneal topography, esthesiometry, pachymetry, as well as endothelial cell count were measured before, 1 day, 1 and 6 weeks, as well as 3, 6 and 12 months after surgery. RESULTS: 3 of 28 grafts showed primary graft failure. For 19 eyes (no other vision-limiting diseases), the best-corrected visual acuity rose on average from 1.0 +/- 0.53 to 0.4 +/- 0.20 (logMAR) 1 year after surgery. The surgically induced astigmatism changed from 3.8 +/- 2.8 dpt preoperatively to 1.4 +/- 1.0 dpt 12 months after DSEK. The pachymetry measured by slit lamp showed an averaged thickness of 649 +/- 54 mm pre- and 776 +/- 75 mm one week and 636 +/- 79 mm 1 year after surgery was performed. The endothelial cell count of the grafts was 2615 +/- 156 cells/mm (2), after one year postoperatively the mean endothelial cell count was 2084 +/- 536 cells/mm (2). The esthesiometry showed a slight rise from 0.96 +/- 0.34 g/mm (2) pre- to 0.96 +/- 0.03 g/mm (2) one year post-surgery. CONCLUSIONS: The postoperative course of our patients shows that improvement of visual acuity by PLK with manually dissected donor tissue is possible. |
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Authors:
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K K Weller; J D Unterlauft; G Geerling |
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Publication Detail:
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Type: Clinical Trial; English Abstract; Journal Article Date: 2010-06-17 |
Journal Detail:
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Title: Klinische Monatsblätter für Augenheilkunde Volume: 227 ISSN: 1439-3999 ISO Abbreviation: Klin Monbl Augenheilkd Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-18 Completed Date: 2010-10-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0014133 Medline TA: Klin Monbl Augenheilkd Country: Germany |
Other Details:
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Languages: ger Pagination: 460-6 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart, New York. |
Affiliation:
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Klinik und Poliklinik für Augenheilkunde, Julius-Maximilians-Universität Würzburg, Würzburg. |
Vernacular Title:
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1-Jahres-Ergebnisse nach posteriorer lamellärer Keratoplastik mit manuell disseziertem Spendermaterial. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Corneal Transplantation / methods* Dissection / methods* Female Humans Male Tissue Donors* Treatment Outcome Vision Disorders / diagnosis*, surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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