| 1-Hydroxypyrene levels in coal-handling workers at a coke oven. | |
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MedLine Citation:
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PMID: 8941904 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An environmental and medical survey was conducted at the coal-handling area of a coke oven, where workers came in contact with coal-tar sludge. The purpose of the study was to determine if skin contact with coal-tar sludge was an important route of exposure to pyrene because workers were observed to have substantial contact with the sludge. Environmental monitoring revealed minimal airborne exposure to pyrene, a byproduct of the coke distillation process; only one personal breathing zone sample detected pyrene, and at least of 0.001 mg/m3. However, the mean preshift urinary 1-hydroxypyrene concentration was 1.00 mumol/mol creatinine (range, 0.16 to 2.96 mumol/mol creatinine) and the mean postshift level was 1.7 mumol/mol creatinine (range, 0.24 to 4.85 mumol/mol creatinine) (P < 0.01). These levels probably reflect absorption as a result of skin exposure. |
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Authors:
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R Malkin; M Kiefer; W Tolos |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine Volume: 38 ISSN: 1076-2752 ISO Abbreviation: J. Occup. Environ. Med. Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1997-05-15 Completed Date: 1997-05-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9504688 Medline TA: J Occup Environ Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1141-4 Citation Subset: IM |
Affiliation:
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Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Air Pollution / analysis Biological Markers Coal Tar / adverse effects* Coke* Humans Keratolytic Agents / adverse effects* Male Occupational Exposure / analysis* Pyrenes / metabolism* Respiratory Protective Devices Skin Absorption* Smoking |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Coke; 0/Keratolytic Agents; 0/Pyrenes; 5315-79-7/1-hydroxypyrene; 8007-45-2/Coal Tar |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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